Gastrointestinal stromal tumor (GIST) ICD 8936/3
KIT-mutated GIST
- GIST882 (KIT Exon 13 mutated GIST)
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- GIST882B (subline of GIST882 - KIT negative)
- GIST-T1 (KIT Exon 11 mutated GIST)
- GIST430 (KIT Exon 11 + 13 mutated GIST)
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- GIST430-11 (subline of GIST430, only exon 11 mutated)
- GIST48 (KIT Exon 11 + 17 mutated GIST)
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- GIST48B (subline of GIST48 - KIT negative)
There are different types of isogenic sublines available: CRISPR sublines and IM-resistant GIST-T1 sublines created by selective pressure.
PDGFRa-mutated GIST
- PDGFRa-mutated GIST-T1 sublines available (see list of CRISPR sublines)
- no cell lines registered yet
NF1-mutated GIST
- no cell lines registered yet
Wildtyp GIST
- no cell lines registered yet
NTRK-GIST
- no cell lines registered yet
Down here you can exchange information about GIST models (questions, comments, problems, etc).
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