sarcoma PDX models

Below you can find all available PDX models from different research groups sorted by the WHO classification (5th edition). More information about the models can be found in the datasheets.

If you are interested in a model, please contact the corresponding researcher directly (contact information can be found in the datasheets).

JOIN THE HUSARC INITIATIVE: If you would like to participate in the HUSARC project by making your sarcoma models available to other researchers, please contact us (contact@husarc.org).

Saroma subtypes sorted by the WHO classification (5th edition)

Adipocytic tumours

Atypical lipomatous tumour 8850/1
Dedifferentiated liposarcoma LPS 8858/3
Epithelioid liposarcoma 8854/3
Inflammatory liposarcoma 8851/3
Lipoma-like liposarcoma 8851/3
Liposarcoma, well-differentiated, NOS 8851/3
Myxoid liposarcoma 8852/3
Myxoid pleomorphic liposarcoma 8859/3
Pleomorphic liposarcoma 8854/3
Sclerosing liposarcoma 8851/3

Fibroblastic and myofibroblastic tumours

Abdominal fibromatosis 8822/1
Dermatofibrosarcoma protuberans NOS DFSP 8832/1
Dermatofibrosarcoma protuberans with myoid differentiation 8832/3
Dermatofibrosarcoma protuberans, fibrosarcomatous 8832/3
Desmoid-type fibromatosis 8821/1
Epithelioid inflammatory myofibroblastic sarcoma 8825/1
Epithelioid myxofibrosarcoma 8811/3
Extra-abdominal desmoid 8821/1
Fat-forming (lipomatous) solitary fibrous tumour 8815/1
Fibrosarcoma NOS 8810/3
Giant cell fibroblastoma 8834/1
Giant cell-rich solitary fibrous tumour 8815/1
Infantile fibrosarcoma 8814/3
Inflammatory myofibroblastic tumour 8825/1
Lipofibromatosis 8851/1
Low-grade fibromyxoid sarcoma 8840/3
Myofibroblastic sarcoma 8825/3
Myxofibrosarcoma MFS 8811/3
Myxoid dermatofibrosarcoma protuberans 8832/3
Myxoinflammatory fibroblastic sarcoma 8811/1
Palmar/plantar-type fibromatosis 8813/1
Pigmented dermatofibrosarcoma protuberans 8833/1
Plaque-like dermatofibrosarcoma protuberans 8832/3
Sclerosing epithelioid fibrosarcoma 8840/3
Solitary fibrous tumour NOS SFT 8815/1
Solitary fibrous tumour, benign 8815/0
Solitary fibrous tumour, malignant 8815/3
Superficial CD34-positive fibroblastic tumour 8810/1

So-called fibrohistiocytic tumours

Giant cell tumour of soft parts NOS 9251/1
Malignant tenosynovial giant cell tumour 9252/3
Plexiform fibrohistiocytic tumour 8835/1

Vascular tumours

AIDS-associated Kaposi sarcoma 9140/3
Angiosarcoma 9120/3
Classic indolent Kaposi sarcoma 9140/3
Composite haemangioendothelioma 9136/1
Endemic African Kaposi sarcoma 9140/3
Epithelioid haemangioendothelioma NOS 9133/3
Epithelioid haemangioendothelioma with WWTR1-CAMTA1 fusion 9133/3
Epithelioid haemangioendothelioma with YAP1-TFE3 fusion 9133/3
Glomus tumour, malignant 8711/3
Kaposi sarcoma 9140/3
Kaposiform haemangioendothelioma 9130/1
latrogenic Kaposi sarcoma 9140/3
Neuroendocrine composite haemangioendothelioma 9136/1
Papillary intralymphatic angioendothelioma 9135/1
Pseudomyogenic (epithelioid sarcoma-like) haemangioendothelioma 9138/1
Retiform haemangioendothelioma 9136/1

Smooth muscle tumours

Leiomyosarcoma NOS LMS 8890/3

Skeletal muscle tumours

Alveolar rhabdomyosarcoma RMS 8920/3
Congenital spindle cell rhabdomyosarcoma with VGLL2/NCOA2/CITED2 rearrangements 8912/3
Ectomesenchymoma 8921/3
Embryonal rhabdomyosarcoma NOS 8910/3
Embryonal rhabdomyosarcoma, pleomorphic 8910/3
Intraosseous spindle cell rhabdomyosarcoma (with TFCP2/NCOA2 rearrangements) 8912/3
MYOD1-mutant spindle cell / sclerosing rhabdomyosarcoma 8912/3
Pleomorphic rhabdomyosarcoma NOS 8901/3
Spindle cell rhabdomyosarcoma 8912/3

Gastrointestinal stromal tumours

Gastrointestinal stromal tumour GIST 8936/3

Chondro-osseous tumours

Osteosarcoma, extraskeletal 9180/3

Peripheral nerve sheath tumours

Granular cell tumour, malignant 9580/3
Malignant peripheral nerve sheath tumour NOS MPNST 9540/3
Malignant peripheral nerve sheath tumour, epithelioid 9542/3
Melanotic malignant peripheral nerve sheath tumour 9540/3
Perineurioma, malignant 9571/3

Tumours of uncertain differentiation

Angiomyolipoma, epithelioid 8860/1
Atypical fibroxanthoma 8830/1
Classic epithelioid sarcoma 8804/3
Clear cell sarcoma NOS CSS 9044/3
Desmoplastic small round cell tumour 8806/3
Epithelioid sarcoma 8804/3
Extraskeletal myxoid chondrosarcoma 9231/3
Haemosiderotic fibrolipomatous tumour 8811/1
Intimal sarcoma 9137/3
Mixed tumour NOS 8940/0
Mixed tumour, malignant, NOS 8940/3
Myoepithelial carcinoma 8982/3
Myoepithelioma NOS 8982/0
Ossifying fibromyxoid tumour NOS 8842/0
Ossifying fibromyxoid tumour, malignant 8842/3
Perivascular epithelioid tumour, malignant 8714/3
Phosphaturic mesenchymal tumour, malignant NTRK-rearranged spindle cell neoplasm (emerging) 8990/3
Pleomorphic sarcoma, undifferentiated UPS 8802/3
Proximal or large cell epithelioid sarcoma 8804/3
Rhabdoid tumour NOS 8963/3
Round cell sarcoma, undifferentiated 8803/3
Spindle cell sarcoma, undifferentiated 8801/3
Synovial sarcoma NOS 9040/3
Synovial sarcoma, biphasic 9043/3
Synovial sarcoma, poorly differentiated 9043/3
Synovial sarcoma, spindle cell 9041/3
Undifferentiated sarcoma 8805/3

Undifferentiated small round cell sarcomas of bone and soft tissue

CIC-rearranged sarcomas 9367/3
Ewing sarcoma 9364/3
Round cell sarcoma with EWSR1-non-ETS fusions 9366/3
Sarcoma with BCOR genetic alterations 9368/3

Chondrogenic tumours

Atypical cartilaginous tumour 9222/1
Chondromatosis NOS 9220/1
Chondrosarcoma, grade 1 9222/3
Chondrosarcoma, grade 2 9220/3
Chondrosarcoma, grade 3 9220/3
Clear cell chondrosarcoma 9242/3
Dedifferentiated chondrosarcoma 9243/3
Mesenchymal chondrosarcoma 9240/3
Periosteal chondrosarcoma 9221/3

Osteogenic tumours

High-grade surface osteosarcoma 9194/3
Low-grade central osteosarcoma 9187/3
Osteoblastoma NOS 9200/1
Osteosarcoma NOS (Conventional osteosarcoma, Telangiectatic osteosarcoma, Small cell osteosarcoma) 9180/3
Parosteal osteosarcoma 9192/3
Periosteal osteosarcoma 9193/3
Secondary osteosarcoma 9184/3

Fibrogenic tumours

Desmoplastic fibroma 8823/1
Fibrosarcoma NOS 8810/3

Vascular tumours of bone

Angiosarcoma 9120/3
Epithelioid haemangioendothelioma NOS 9133/3
Epithelioid haemangioma 9125/0

Osteoclastic giant cell-rich tumours

Giant cell tumour of bone NOS 9250/1
Giant cell tumour of bone, malignant 9250/3

Notochordal tumours

Chordoma NOS (Chondroid chordoma) 9370/3
Dedifferentiated chordoma 9372/3
Poorly differentiated chordoma 9370/3

Other mesenchymal tumours of bone

Adamantinoma of long bones (Dedifferentiated adamantinoma) 9261/3
Leiomyosarcoma NOS 8890/3
Mesenchymoma NOS 8990/1
Osteofibrous dysplasia-like adamantinoma 9261/1
Pleomorphic sarcoma, undifferentiated (Bone metastases) 8802/3