Gastrointestinal stromal tumor (GIST) ICD 8936/3

GIST430

(Synonyms: GIST-430 ; GIST 430)

HUSARC Accession Number: HU-21.3

Plot displays IC50 values for Inhibitors

KIT; Exon 11 ; p.Val560_Leu576del (c.1678_1728del) (ClinVar=VCV000523644) ; Exon 13; p.Val654Ala (c.1961T>C); Zygosity=Heterozygous (Cosmic: COSS1180674)

GEO accession GSE19399 (Affymetrix 250K StyI SNP array data)
GEO accession GSE95862 (Illumina NextSeq 500)
GEO accession GSE95863 (Illumina NextSeq 500)
GEO accession GSE95864 (Illumina NextSeq 500)

More information about the models can be found in the datasheets.

datasheet GIST430

If you are interested in a model, please contact the corresponding researcher directly (contact information can be found below and in the datasheet).

Heinrich MC, Corless CL, Blanke CD, Demetri GD, Joensuu H, Roberts PJ, Eisenberg BL, von Mehren M, Fletcher CD, Sandau K, McDougall K, Ou WB, Chen CJ, Fletcher JA. Molecular correlates of imatinib resistance in gastrointestinal stromal tumors. J Clin Oncol. 2006 Oct 10;24(29):4764-74. DOI: 10.1200/JCO.2006.06.2265. Epub 2006 Sep 5. PMID: 16954519.

Registered by Bauer-Lab (Essen, Germany)

Entry creation: 14.09.2021

Last entry update: 08.11.2021

Version number: #1